请问有了解TMS（交变经颅磁刺激）治疗方案的吗

bashan

我昨天在北医六院的橱窗里看到了有关TMS治疗的介绍：
“美国加州大学资深专家金怡教授通过多年的研究，发现大脑节律性活动对于正常认知功能至关重要，而孤独症患者都有不同程度的脑节律活动障碍。金怡教授以科学的研究手段发明了以交变经颅磁刺激（TMS）结合高端脑电检查（EEG）的无创性治疗方法。该方法能够对精神疾患、包括孤独症患者的脑电节律进行全面的调谐，从而从根本上改变患者大脑的工作状态。
  TMS这一个新型无创性治疗技术在中国、加拿大、法国及其他欧洲国家和地区已经被正式列为临床治疗项目。现金怡教授与北京大学第六医院和北京明哲医院合作，希望通过这种安全的物理刺激有效地在不同程度地改善孤独症患者的认知功能、语言交流、社会交往及情绪行为异常，且无明显的副作用。促进患儿的康复，改善患儿的预后，为患儿和家长带来更多的希望。"
有了解这方面的的资讯的星妈星爸吗？能否给个建议？谢谢！

thanxgod

很感兴趣，查了一下。FDA已经同意用于治疗（限于off label）。

Where have Transcranial Magnetic Stimulation (TMS) and MERT been researched?
Transcranial Magnetic Stimulation (TMS) was developed in England and is currently being actively investigated at major universities throughout the world such as Harvard, Yale, Georgetown University Medical Center, The Medical University of South Carolina, Stanford University, Helsinki University Central Hospital, University of California Irvine and the University of Sydney.

Has MERT (Transcranial Magnetic Stimulation - TMS) been approved by regulatory agencies?
Several TMS/rTMS devices are approved by the US Food and Drug Administration (FDA) for stimulation of peripheral nerve and, therefore, can be used "off label" by individual physicians to treat brain disorders, essentially in any way they believe appropriate, analogous to the off label use of medications. In January of 2007, the FDA抯 Neurological Devices Panel concluded that Transcranial Magnetic Stimulation (TMS) treatment is safe but requires further research to demonstrate efficacy. Recently, at the end of 2008, Transcranial Magnetic Stimulation (TMS) was approved by the FDA for treatment.

In 2002, Health Canada approved Transcranial Magnetic Stimulation (TMS) as a treatment for medication-resistant depression.

Will insurance pay for MERT?
Because MERT (Transcranial Magnetic Stimulation - TMS) was not approved by the FDA until recently, most U.S. insurance companies will not pay for MERT (Transcranial Magnetic Stimulation - TMS) treatments.

Is MERT (Transcranial Magnetic Stimulation - TMS) safe? Are there any common side effects?
Transcranial Magnetic Stimulation (TMS) was introduced in the mid 1980s. It is generally agreed to be free from side effects when proper procedures are followed. Over the years since introduction, safety guidelines have been developed which minimize risks. The main complaint from a small percentage of patients is headache during and immediately following the stimulation session. This can be alleviated with over-the-counter pain medications such as acetomycin (Tylenol), aspirin or ibuprofen. It is believed that these headaches are caused by the inadvertent stimulation of nearby muscle groups, which results in tension headaches. Another common problem is ringing in the ears caused by the noise of the stimulating coil, so earplugs are typically worn during the procedure.

Seizures are the major possible risk associated with Transcranial Magnetic Stimulation (TMS), although they have only been encountered in a few patients thus far. While Transcranial Magnetic Stimulation(TMS) safety guidelines established in 1993 and revised in 1996 go a long way to reducing the chances of seizure, the possibility still exists.

What diseases/disorders have MERT (Transcranial Magnetic Stimulation - TMS) been successful in treating?
Transcranial Magnetic Stimulation (TMS) is currently being studied as a potential treatment for many disorders including depression, schizophrenia, posttraumatic stress disorder, obsessive-compulsive disorder, migraine headaches, autism, stroke, and chronic neuropathic pain. Numerous studies have been published in peer reviewed journals which indicate that Transcranial Magnetic Stimulation (TMS) is even useful in treating cases of depression which are untreatable with any other therapy. Some have called Transcranial Magnetic Stimulation (TMS) a "life saver."

binfeng2000

你上面的内容是从商家那里摘来的吗？ 如果你自己去FDA的网站上查一查这个TMS， 最近的还是这个专家委员会的报告，这个还是用于““The treatment of Major Depressive Disorder (MDD).”一点也没有提到其他的方面，而且这个委员会还认为这个TMS
的安全性还不如以前的产品，现在被宣称用来治疗自闭症了，怎么说的过去？类似的宣传多了，看你自己怎么估计怎么想的了。

秋爸爸

撑死是个科研试验。
国内利用这个“经颅磁刺激”来治疗各种脑病的忽悠有很多种。有的就是为了赚钱。
在自闭症上，不靠谱。

thanxgod

多谢上面两位拍砖。此网页来源于Brookside Institute，确实应该是改学院的广告帖，off lable 就是非适应症的，用于自闭确实有很大问题。查了下金教授的背景 ，原上海第一医科大学毕业。现在UCI的助理教授，uci脑电图谱行为实验室主任。现在在国内搞TMS很可能是科研性质的，不排除估计搞几篇文章，再去申请课题，毕竟国内容易混，可以滚动发展。楼主如果钱超多，时间多，胆子超大，可以去试试，如果不是，还是算了。想当年，一个神经科的教授让我的孩子做波普核磁共振，折腾了我们家够呛，还没有什么用。

myChinaHope

同意各位观点,治自闭症上，不靠谱.我们在美国自闭症上研究这么多也没有听说过这个.

bashan

感谢各位的热心回复！我打算暂时先不做了，谢谢各位！