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re:[QUOTE][b]下面引用由[u]BM...
下面引用由BMW发表的内容:
zc的孩子能不能上大学,要是不能上该去埋怨谁,这些问题我不清楚。反正我的孩子要是上不了高中,我会去埋怨党的“晚生晚育”口号,30好几了才生第一个孩子。这也是为什么我听说杨教授怀孕了的时候特别担心。不禁...
你这个埋怨是有依据的,有人专门研究了这个:
自闭症出生比例:
女,生育年龄:40&40以上:1:123 25-29:1:156
男,生育年龄:40&40以上:1:116 25-29:1:176
Autism Research: Older Parents More Likely to Have Autistic Children
Thursday April 5, 2007
A while back, an Israeli study seemed to suggest that older fathers were more likely to have children with autism. That study was significantly flawed, and while it raised media attention it didn't appear to represent a major finding. Now, that research has been supported by a larger, broader study by Kaiser Permanente:
Men and women who wait to have babies later in life may increase their children's risk for autism, according to a Kaiser Permanente study featured in the April issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
The study investigated 132,844 children born at Kaiser Permanente hospitals in its Northern California region over a five-year period (1995-1999) and identified 593 children who had been diagnosed with an autism spectrum disorder (ASD).
Study results show that a mother's and father's risk of delivering a child with autism steadily increases as they get older. Women ages 40 and older showed a 30 percent increase in risk for having a child with autism (1 in 123), when compared to moms between the ages of 25 and 29 (1 in 156). Men ages 40 and older had up to a 50 percent increased risk of having a child with autism (1 in 116), when compared to their 25- to 29-year-old peers (1 in 176).
Advanced age of mothers has been associated with risk of autism in several, but not all earlier studies, according to study author Lisa A. Croen, PhD, an epidemiologist at Kaiser Permanente's Division of Research in Oakland, Calif. The role of a father's age in autism has been less frequently studied, although advanced paternal age has been associated with other adverse reproductive outcomes, including miscarriage, childhood cancers, autoimmune disorders, schizophrenia and other neuro-psychiatric disorders.
This study seems to be supported by a recent announcement that some cases of autism may be caused by spontaneous mutations in hundreds of different genes:
"As men age, there is an increased frequency of new mutations in the cells that go on to become sperm," said Dr. Croen. "These sporadic mutations could be related to autism risk. It is possible that non-genetic factors that are more common in older parents might also account for our findings."
Could older parents really be a contributing cause to the rise in autism? If so, it seems to be the case only for a portion of the cases being diagnosed. Even so, it's cause for concer - especially for older parents who already have one child on the autism spectrum.
Are you concerned about this new research? Please share your thoughts! |
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